Issues List

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1018DefectSkylineAdducts should not attempt formula math when the molecule is described as mass onlyGuest3closed 
1017DefectSkylineMenuitem enabling needs cleanup for Spectrum Match settingsRita Chupalov3open23.2
1016TodoSkylineUse new "Associate Proteins" dialog in other places proteins are associatedMatt Chambers3open 
1015DefectSkylineGlycan idotp values incorrect until close and re-open documentBrendan MacLean3resolved23.2
1014DefectSkylineImmediate Window does not support ESC to focus the Targets ViewBrendan MacLean3open23.2
1013TodoSkylineConsider adding ability to filter MS/MS during DDA import peptide searchMatt Chambers3open23.2
1012DefectSkylineRatio to Heavy not available in small molecule mode until heavy precursors addedBrian Pratt3open23.2
1011DefectSkylineOut of Memory Error for Yeast.hlf in MethodEdit tutorial on Polish systemBrendan MacLean2open23.2
1010TodoSkylineAdd shortcuts for Peptide Settings and Transition SettingsBrendan MacLean2open23.2
1009DefectSkylinebottleneck in spectral library viewer when attempting to access ion mobility valuesBrian Pratt3open 
1008DefectSkylineinclude more .D metadata in Skyline replicatesMatt Chambers3open 
1007DefectSkylineModificationMatcher over guesses with Acetyl modificationsBrendan MacLean2resolved23.2
1006DefectSkylineImportTransitionListColumnSelectDlg too trusting of column header namesBrian Pratt3open23.2
1005TodoSkylineAdd support for setting Settings > Integrate All from the command-lineMatt Chambers2open23.2
1004TodoSkylineAdd support for adding modifications from the command-lineBrendan MacLean2open23.2
1003DefectSkylineFix TransitionGroup.GetTransitions() for small molecules to use library information when availableBrendan MacLean3open23.2
1002DefectSkylinetrouble with transition list created with our own document grid exportBrian Pratt3open 
1001DefectSkylineneed exceptiion handling for bad MoleculeMassOffset.SplitFormulaAndMasses inputBrian Pratt3open 
1000DefectSkylineWhen reading peptide transition lists we should offer to apply document settings - adding reporter ions, other precursor charges etc.Brendan MacLean3open 
999DefectSkylineInvestigate using ExcludeFromAssay field from DIA-NNBrendan MacLean3open 
998DefectSkylineFix issues with matching DIANN speclib to report TSVMatt Chambers3open 
997DefectSkylineWe should allow adducts with formulaic losses on mass-only molecule description (e.g. don't complain that Adduct "[M-CO2]-" calls for removing more C atoms than are found in the molecule [+331.977251])Brian Pratt3open 
996TodoSkylineFeature detection could be reworked to parallelize tasksBrian Pratt3open 
995TodoSkylineImport Peptide Search should default to no decoys when Library.UseExplicitPeakBounds will be usedMatt Chambers3open23.2
994TodoSkylineFile > Import > Peptide Search - FASTA page should have Peptide Settings - Filter optionsMatt Chambers3open23.2
993DefectSkylineWeirdness in the raw data view when switching from IM-containing replicate to non-IM replicateRita Chupalov3open23.2
992DefectSkylineDIA-NN Speclib handling in BlibBuild mishandles n-terminal modsGuest2closed23.2
991DefectSkylineWe should add a "Run" submenu to Skyline's File menu, and move Feature Detection, Encyclopedia, and peptide search engines there from the "Import" menuBrian Pratt3open 
990TodoSkylineClean up Transition Settings and IMS arguments in command-line documentationBrian Pratt3open23.2
989TodoSkylineNeed to add new coverage for Peptide Settings changes by command-lineGuest1closed23.2
988DefectSkylineNeed to normalize Transition Settings change command-line outputGuest3closed23.2
987DefectSkylineDisplaying tooltip for protein sometimes takes a really long time when "Enforce Uniqueness" is enabledBrian Pratt3open 
986DefectSkylineMake ion mobility library editor searchableBrian Pratt3open 
985DefectSkylineTarget tree's Find function results window says "Peptide" where it should say "Molecule"Brian Pratt3open 
984DefectSkyline"zombie chromatograms" complicate merging of Skyline filesNick Shulman3open 
983DefectSkylinemanually modifying molecule mass does not modify the m/z of precursor transitions belowBrian Pratt3open 
982TodoSkylineImproved error message when user tries to File>Open a mass spec data file in SkylineBrian Pratt3open 
981DefectSkylineCE optimization does not work for SCIEX QTOF instrumentsMatt Chambers3open 
979DefectSkylineSupport isotope nomenclature like "[13C]3H7[15N]O2" (that's C'3H7N'O2 in Skyline-speak)Brian Pratt3open 
978DefectSkylineNeed a way to represent targets that were dimers in the IMS stage but broke into monomers in the MS stageBrian Pratt3open 
977DefectSkylineNeed a way to import and display keys other than InChI, SMILES, KEGG etc - e.g. "METLIN ID"Brian Pratt3open 
976DefectSkylineLibrary Explorer: Allow for searching within peptide/molecule descriptionBrian Pratt3open 
975TodoSkylinefeature request: User-editable keyboard shortcuts for menu itemsBrendan MacLean3open 
974DefectSkylineOpenDataSourceDialog WIFF/WIFF2 data type causes file selection to be painfulBrendan MacLean2resolved23.2
973TodoSkylineAdd a way to add annotation definitions to a Skyline document from the command-linehenrytsanford2open23.2
972DefectSkylineFeature: Export mProphet features from commandlinehenrytsanford3open 
971DefectSkylineSmall molecule transition list reader could be more clever about setting formulasBrian Pratt3open 
970TodoSkylineFeature request: Right click on molecule in the molecule tree to “Add to iRT Database”Brendan MacLean3open 
969DefectSkylineTrouble handling transition lists that declare precursor isotopesBrian Pratt3open 
968DefectSkylineNullReferenceException when uploading to a saved Panorama URIVagisha Sharma3open 
967DefectSkylineCreate matching small molecule versions of all standard peptide reports in Document GridGuest3closed 
966TodoSkyline"Mobiligram" display for ion mobility filtered chromatograms (alternate view to our ion mobility heatmap)Rita Chupalov3open 
965TodoSkylineAdd command arg to SkylineRunner.exe to run any instance of Skyline by pathBrendan MacLean3open23.2
964DefectSkylineFeature Request - Surrogate calibration curvesGuest3closed 
963DefectSkylineFeature Request - Remove Replicate/Result from Chromatogram or Replicate Right-click menuBrendan MacLean3open 
962DefectSkylineFind CCS values for targets not found in an IMSDB library without changing existing valuesBrendan MacLean3open 
961TodoSkylineShow units for pressure traces in Skyline chromatograms and enable Panorama to do the sameMatt Chambers3open23.2
960DefectSkylineChinese language update: "Centroided" in the drop down list can be translated as 中心对称的Brendan MacLean2open23.1
959TodoSkylineImprove error message for BlibBuild failuresBrendan MacLean2resolved23.1
958DefectSkylineadd the Skyline version to the "More Info" text in alert dialogsGuest3closed 
957TodoSkylineDuplicated collision energy settings for SCIEX instrumentsRita Chupalov3open 
956DefectSkylineSupport for importing results from the Sage search engineBrian Pratt3open 
955DefectSkyline"Associate Proteins" should not remove unmapped peptides from the document.Guest2closed23.1
954DefectSkylinesome interesting small molecule transition list weirdnessBrian Pratt3open 
953DefectSkylineadd a code inspection test to check that the start page Tutorials tab uses the same links as the Tutorials testsBrian Pratt3open 
952TodoSkylineStrategies for reducing ExceptionWeb reports for already-solved issuesBrian Pratt3open 
951DefectSkylineSpectral Library ion mobility values don't work intuitively in document grid and method exportBrendan MacLean3open 
950TodoSkylineInvestigate more efficient sorting of three-array IMS scans - possibly the locally sorted "sawtooth" nature of the mz could be exploitedGuest3closed 
949DefectSkylinePeak Areas > Peptide Comparison view should not show a "heavy" pane with nothing in itBrendan MacLean3resolved23.1
948TodoSkylineMake Import Assay Library work for small moleculesBrian Pratt3open 
947DefectSkylineIMS spectrum viewer less reliable than it used to beBrendan MacLean2resolved22.2
946TodoSkylineRenaming a molecule in small molecules breaks associationsGuest2closed 
945TodoSkylineAdd a splitter to Unique Peptides formBrendan MacLean3resolved 
944DefectSkylinePeak area plotting still deceiving when transforms are applied to the chromatogramsBrendan MacLean3resolved 
943DefectSkylineImporting BLIB into IMSDB, we should take mean of multiple IM values instead of creating multiple entriesBrian Pratt3open 
942TodoSkylineAdd Start Time and End Time to spectrum propertiesRita Chupalov3open23.1
941DefectSkylineRed and green dots in Targets tree should be customizable colors, or different shapesMark Belanger3open 
940DefectAutoQCAdd sample file filtering option to AutoQC LoaderVagisha Sharma3open 
939DefectSkylineOff-by-one in Enzyme.GetMatches() dealing with protein C-terminusGuest3closed23.1
938TodoSkylineAdd property sheets to spectrum graphsBrendan MacLean2resolved23.1
937DefectSkylineDIA Umpire tests are much slower for languages with a comma decimal separatorMatt Chambers2open23.1
936TodoSkylineThermo Eclipse and Fusion Lumos method exportKaipo Tamura3resolved23.1
935DefectSkylineCapture injection time as sample-scoped chromatogramBrendan MacLean3open 
934TodoSkylineEnable optimization method export for more TOF instrumentsKaipo Tamura2open 
933TodoSkylineThorium method exportKaipo Tamura2open 
932TodoTestResultsSummarize/graph pass1 iteration count for testsKaipo Tamura4open 
931TodoSkylineAgilent MH 12 method exportKaipo Tamura2open 
930TodoSkylineExport isolation list (DIA) for Bruker timsTOFKaipo Tamura4open 
929DefectSkylineWhen explicit ion mobility values are used, the reported CCS value should be adjusted appropriately in the resulting chromatogram extractionsGuest3closed 
928DefectSkylineAssumptionException saving document with protein groups sometimesGuest2closed23.1
927DefectSkylineBibliospec - retain fragment charge values in MGF filesBrian Pratt3open 
926TodoSkylineImplement Bruker Paser support in BlibBuildBrendan MacLean2resolved23.1
925DefectSkylineTargets view hangs during mouse-over with peptides longer than 2000 or soNick Shulman3open 
924DefectSkylineFix ability to provide a protein description in Edit > Insert > PeptidesNick Shulman3open 
923TodoSkylineImplement an interface that allows for multiple algorithms to do peak group assignmentNick Shulman3open 
922DefectSkylineEdit > Find needs to use LongWaitDlg and support cancelBrendan MacLean3resolved23.1
921TodoSkylineTransition list reader should identify special ions by m/z the same way it does calculated peptide fragment ionsBrendan MacLean3open 
920DefectSkylineWhen Group By fails in replicate comparison graphs you lose the Order By menu itemNick Shulman3open23.1
919DefectSkylineSpectrumLibraryInfoDlg scoring columns should match library build columnsBrendan MacLean3resolved23.1
918DefectSkylinea few issues with "Use Results" in ion mobility librariesBrian Pratt3open23.1