Issue 1013: Consider adding ability to filter MS/MS during DDA import peptide search

issues
Status:open
Assigned To:Matt Chambers
Type:Todo
Area:Skyline
Priority:3
Milestone:23.2
Opened:2024-03-06 00:42 by Brendan MacLean
Changed:2024-03-06 00:42 by Brendan MacLean
Resolved:
Resolution:
Closed:
2024-03-06 00:42 Brendan MacLean
Title»Consider adding ability to filter MS/MS during DDA import peptide search
Assigned To»Matt Chambers
Notify»Nick Shulman
Type»Todo
Area»Skyline
Priority»3
Milestone»23.2
During a tutorial on importing DDA data into Skyline at Dortmund, the instructor pointed out that it is not possible to specify MS/MS extraction in the Import > Peptide Search wizard. We now support a "DDA" isolation scheme where we add fragment transitions that are marked as non-quantitative. And we may soon use that for TMT processing with relative quant based on reporter ions in the MS/MS.

We probably need to add the MS/MS extraction parameters as optional to the wizard. Maybe they should just have the MS/MS "Acquisition method:" combo box with the options "None" and "DDA" as in Transition Settings to allow the user to choose either to include MS/MS transitions or not. This is different from DIA and PRM where MS/MS transitions are required and "Acquisition method" is assumed from the choice. Though, DIA shows the "Acquisition scheme" combo, which PRM does not and DDA would not.