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Senior Scientist - Computational Biologist | |||
liang xue | 2024-04-12 14:07 | ||
Application link: https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---Massachusetts---Cambridge/Senior-Scientist---Computational-Biologist_4909646-2 Job Summary: The Senior Scientist Computational Biologist will be a key member of the Machine Learning and Computational Sciences Team, focusing on the analysis and interpretation of complex datasets generated from omics experiments to drive drug discovery and development. The role will require applying a deep understanding of biology together with advanced computational methods to solve complex biological problems and contribute to the understanding of disease mechanisms at the molecular level. The successful candidate will demonstrate an enthusiasm to work, collaborate, and communicate with both computational and experimental colleagues. Key Responsibilities: Qualifications: Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Work Location Assignment: Cambridge, MA, USA On Premise/Hybrid | |||
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PhD student (f/m/d) in the group “Translational Mass Spectrometry and Biomarker Research (Oeckl lab)” at the German Center for Neurodegenerative Dieseases (DZNE) in Ulm, Germany | |||
patrick oeckl | 2023-10-30 06:04 | ||
The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine (www.dzne.de). For the DZNE site in Ulm, we are inviting applications for a PhD student (f/m/d) in the group “Translational Mass Spectrometry and Biomarker Research (Oeckl lab)” Code – 6033/2023/10 The Oeckl lab (www.oeckllab.com) uses state-of-the-art mass spectrometry for the discovery, characterization and implementation of fluid biomarkers (blood, cerebrospinal fluid) for neurodegenerative diseases such as Alzheimer´s disease, amyotrophic lateral sclerosis (ALS) or frontotemporal dementia. We use proteomic/peptidomic approaches in patient samples to discover novel biomarker candidates which might improve (early/differential) diagnosis, disease monitoring or drug development (e.g. Oeckl et al., Acta Neuropathol 2020). To characterize specific biomarker candidates and the related pathomechanisms in detail (e.g. synaptic marker beta-synuclein in blood), we develop highly sensitive and accurate methods using targeted mass spectrometry (MRM, PRM, IP-MS) to study samples from large patient cohorts and evaluate their value for use in the clinic or drug development (e.g. Oeckl et al., Alzheimers Dement 2023). These assays are also intended to be used as reference measurement procedures in round robins and biomarker implementation. For promising biomarker candidates, we also develop highly sensitive immunoassays (ELISA, Simoa, Ella) for routine clinical application. The association of the Oeckl lab to the Neurology Department of the Ulm University Hospital provides excellent interaction with neurologists and psychologists and access to well-characterized patient samples enabling highly clinically-oriented research. We have our own equipment for highly competitive biomarker research including state-of-the-art mass spectrometry (Exploris 480 with FAIMS, QTRAP6500), immunoassay instruments (Simoa, Ella) and devices for sample handling (e.g. KingFisher Apex, Viaflo96). Your tasks Requirements The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and Please apply via: | |||
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Senior Research Support Specialist with a focus on Metabolomics | Proteomics Resource Center Organization Overview | |||
henrik molina | 2023-09-18 07:19 | ||
The Proteomics Resource Center (PRC) at The Rockefeller University masters many aspects of liquid chromatography/mass spectrometry applied to metabolomics and proteomics. Examples include de novo sequencing, and quantitative analysis based on label-free quantitation as well as heavy isotope labeled samples. The PRC is equipped with Orbitrap-type mass spectrometers (high resolution/high mass accuracy) and can separate analytes using both nano and high-flow liquid chromatography. The Center is a source for help with planning of mass spectrometry-based experiments, and it has the capability to offer in-depth collaborative analysis. Also, the PRC is operated in a boutique style, encouraging the scientists of the Center to work closely with users to create a tailored approach to fit the many unique questions that can be answered by analytical mass spectrometry. The Center is equipped with multiple high-performance servers for data analysis. Overview Responsibilities Qualifications Preferred: Rockefeller University does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy, gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service or other non-merit factor. All qualified applicants will receive consideration for employment without regard to the characteristics listed above. Compensation Range: USD $90,000.00/Yr. to USD $120,000.00/Yr. | |||
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Junior Group leader for mass spectrometry at the Institute of Biochemistry, Faculty of Medicine, JLU Giessen | |||
lienhard schmitz | 2023-08-10 06:14 | ||
Commencing in 2024, a position is available at the Department of Biochemistry within the Faculty of Medicine, offering the possibility to establish an independent research group. The position is initially limited to 6 years, but it can be made permanent upon fulfilling the corresponding requirements. The junior group leader will conduct own research projects and develop new applications in protein mass spectrometry. In addition the scientist will provide technical mass spectrometry support for other researchers. The position will be supported by a technician. Active participation in teaching, as well as acquiring third-party funding, is expected. The opportunity for habilitation is provided upon fulfilling the necessary requirements. The salary is in accordance with the collective labour agreement of the State of Hessen. For more information, please contact Prof. Lienhard Schmitz | |||
Job description mass spectrometry.pdf 00_Ausschreibungstext E.pdf | |||
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