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Senior Proteomics Scientist
DWANG 2019-01-15

Newomics Inc., a venture-backed and NIH-funded commercial-stage biotechnology company in the San Francisco Bay Area, develops and commercializes enabling platforms and solutions for precision medicine. Newomics has unique infrastructure and resources to make major contributions to personalized healthcare. For more information, visit www.newomics.com.

Newomics has an immediate opening for a full-time Senior Proteomics Scientist position. Outstanding candidates will be considered at the Principal Scientist level. Newomics will provide a comprehensive compensation package including salary, equity, and benefits such as PTO, medical/dental/vision and 401(k) plan etc.

Responsibilities
• Lead the development and commercialization of cutting-edge multiomics assays
• Support the development and commercialization of Newomics microfluidic chips
• Develop global multiomics workflows for assays of biological samples
• Perform LC-MS analysis of proteins, peptides, and small molecules in biological samples
• Work with team members on LC-MS applications of microfluidic devices
• Perform data analysis with statistical and bioinformatics tools
• Participate in the general lab and instrument maintenance
• Document all experimental records and file reports
• Publish papers in peer-reviewed journals

Qualifications
• A PhD degree in mass spectrometry, analytical chemistry or a related field
• 5+ years of experience in industry or academia after obtaining a PhD degree
• A strong publication record in proteomics or multiomics
• Well-versed in Thermo Scientific mass spectrometers such as QE series and QQQ
• Demonstrated experience in developing global proteomics assays for biological samples
• Extensive hands-on experience in biological sample preparation for nanoflow LC-MS
• In-depth understanding of both hardware and software of nanoflow LC-electrospray MS
• Proficiency in LC-MS related software and data analysis
• Experience in both top-down and bottom-up proteomics is a strong plus
• Experience in working with microfluidic devices is a strong plus
• Highly motivated, a team player, a quick learner, and a problem solver
• Excellent oral and written communication skills
• Ability to work in a fast-paced startup environment
• Eligibility to work in the United States

To apply
Please send a cover letter, resume with the publication list, and contact information for three references, to jobs@newomics.com

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Genentech - Associate Scientist, Biomarker Mass Spectrometry Laboratory - South San Francisco, CA, USA
Veronica Anania 2018-11-01

Apply here: https://www.gene.com/careers/detail/201810-122932/Associate-Scientist-Biomarker-Mass-Spectrometry-Laboratory

We are seeking a highly motivated laboratory-based scientist to join the OMNI Biomarker Development group within Development Sciences. Our group is responsible for designing and implementing biomarker assays using mass spectrometry to support programs in clinical development at Genentech in the disease areas of Immunology, Inflammation and Autoimmune Diseases, Ophthalmology, Metabolism, and Neuroscience.

As a key member of the biomarker mass spectrometry laboratory, the ideal candidate will utilize mass spectrometry to explore novel biomarker hypotheses and support clinical development. Expertise in developing quantitative mass spectrometry assays, experience in clinical sample processing from biological matrices and a strong analytical background is required. Hands-on experience with small or large molecule sample preparation and LC and MS instrumentation is also required.

PhD in Analytical Chemistry, Biochemistry, or Biotechnology
Minimum of 4 years of hands-on experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) (SCIEX and Thermo instruments), and have strong troubleshooting capabilities
Strong analytical background with fundamentals in quantitative assay development and assay evaluation
Knowledge of sample preparation techniques for analysis of drugs, biomarkers and other mediators from biological fluids (e.g. plasma, serum, CSF, urine)
Demonstrated expertise in the quantitative analysis of compounds from biological matrices, especially using HPLC and HPLC-MS techniques
Experience developing quantitative MS techniques (e.g. SRM, MRM, or PRM)
A proven ability to analyze complex datasets using tools like Spotfire, R, or Skyline and experience with standard instrument software such as Analyst or Xcalibur
In addition, the candidate should have excellent communication, presentation, and interpersonal skills, be able to work independently as well as in a team environment, and be willing and eager to learn new technologies

Who We Are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page. At Genentech, we share salary ranges with applicants during the recruiting process, if requested. Third party salary estimates may not be accurate or up-to-date.

 Associate Scientist, Biomarker Mass Spectrometry Laboratory.pdf 
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