Issues List

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1058TodoSkylineAdd more support for chromatogram types in Bruker dataGuest3closed 
1057DefectSkylineAdd a transition list reader column "CNL Spectrum Filter" to simplify working with Constant Neutral Loss scan dataGuest3closed 
1056DefectSkyline"Copy Data" for IMS heatmap display in Full Scan view is brokenGuest3closed 
1055DefectSkylineAlert user when importing ion mobility data when there are IM filter values available (explicit, imsdb, blib) but IM filtering is disabledGuest3closed 
1054DefectSkylineNIST .msp peptide descriptions with n and c terminal notation (e.g. "… …Name: n[43]ALAVLALLSLSGLEAIQR/5" or "Name: AACDEFGHIKc[17]/3") are being ignoredGuest3closed 
1053DefectSkylineTarget tree allows for manual creation of nonsense molecules e.g. "U-H2O"Guest3closed 
1052DefectSkylineAlphaPeptDeep wording suggestionsGuest4closed25.2
1051DefectSkylineToo many LongWaitDlgs during AlphaPeptDeep library buildingGuest3closed25.2
1050DefectSkylineAlphaPeptDeep output files need to be written somewhere outside the Skyline.exe/Tools folderGuest2closed25.2
1049TodoSkylineUsers need to be able to tell Skyline that they have GC EI dataGuest3closed 
1048DefectSkylineRetention Times - Peptide Comparison graph is not UI mode awareGuest3closed 
1047DefectSkylineimprove SkylineCmd's handling of unrecognized transition list column namesGuest3closed 
1046TodoSkylinecommand line needs the ability to remove named replicates from documentGuest3closed 
1045TodoSkylineUsers would like settable colors for each moleculeGuest3closed 
1044TodoSkylineAdd .sdf file support for spectral library creationGuest3closed 
1043DefectSkylineProvide for manual adjustmen of IM integration as we do for RTGuest3closed 
1042TodoSkylineLibrary Explorer should show iRT information when it is present in a BLIB fileGuest3closed24.2
1041DefectSkylineMSGF+ Installation form does not copy textGuest3closed24.2
1040TodoSkylineImport DIA Peptide Search should suggest using a prespecified isolation scheme based on the dataGuest3closed24.2
1039DefectSkylineImport DDA Peptide Search produces different replicate name sort order than Import DIA Peptide SearchGuest3closed24.2
1038TodoSkylineImport DIA Peptide Search never suggests chromatogram extraction filesGuest2closed24.2
1037DefectSkylineDocuments with lots of mods can get very slow for Import > Transition ListGuest3closed24.2
1036TodoSkylineMass spec files contain metadata that could usefully be preserved as annotations on replicates in SkylineGuest3closed 
1035TodoSkylineAdd Mirror and Koina menu options to Full-Scan graphGuest3closed24.2
1034TodoSkylineAdd mirror plot option to chromatogram graphsGuest3closed24.2
1033DefectSkylineFix Normalize To > Heavy Peak Areas - Replicate plot to show rdotp line graphGuest2closed24.2
1032TodoSkylineSkyline needs at least one default report that just gives peak areas for all replicatesGuest3closed24.2
1031DefectSkylineMolecule reports show up in Document Settings - Reports when in proteomics modeGuest3closed24.2
1030DefectSkylineSmall molecule improvements are predicted RTGuest3closed 
1029TodoSkylineIntegrate Carafe into Peptide Settings - Library - BuildGuest2closed24.2
1028TodoSkylineIntegrate AlphaPeptDeep prediction into Peptide Settings - Library - BuildGuest2closed24.2
1027TodoSkylineSkyline DDA Searches that use Percolator need to calculate all-files-q-valuesGuest2closed24.2
1026DefectSkylinePeak Areas - Relative Abundance includes decoys by defaultGuest2closed24.2
1025DefectSkylineFeature finding should provide information in terms of the expected peptides in a document - what's novel in the search result, what's missingGuest3closed 
1024TodoSkylineSupport transition list "Note" import for all node levels (molecule, precursor, transition)Guest3closed 
1023DefectSkylineArgumentOutOfRangeException scrolling "Ion Types" context menuGuest2closed24.2
1022DefectSkylineidFileName column values are not set in minimized libraries.Guest3closed 
1021DefectSkylineDiscourage training mProphet models when explicit peak boundaries are being used from librariesGuest3closed23.2
1020DefectSkylineTransition Full Scan Settings page should discourage user from using retention time filtering with PRMGuest3closed23.2
1019DefectSkylineConfusing behavior of ID lines on chromatograms when library has multiple charge statesGuest3closed23.2
1018DefectSkylineAdducts should not attempt formula math when the molecule is described as mass onlyGuest3closed 
1017DefectSkylineMenuitem enabling needs cleanup for Spectrum Match settingsGuest3closed23.2
1016TodoSkylineUse new "Associate Proteins" dialog in other places proteins are associatedGuest3closed 
1015DefectSkylineGlycan idotp values incorrect until close and re-open documentGuest3closed23.2
1014DefectSkylineImmediate Window does not support ESC to focus the Targets ViewGuest3closed23.2
1013TodoSkylineConsider adding ability to filter MS/MS during DDA import peptide searchGuest3closed23.2
1012DefectSkylineRatio to Heavy not available in small molecule mode until heavy precursors addedGuest3closed23.2
1011DefectSkylineOut of Memory Error for Yeast.hlf in MethodEdit tutorial on Polish systemGuest2closed23.2
1010TodoSkylineAdd shortcuts for Peptide Settings and Transition SettingsGuest2closed23.2
1009DefectSkylinebottleneck in spectral library viewer when attempting to access ion mobility valuesGuest3closed 
1008DefectSkylineinclude more .D metadata in Skyline replicatesGuest3closed 
1007DefectSkylineModificationMatcher over guesses with Acetyl modificationsGuest2closed23.2
1006DefectSkylineImportTransitionListColumnSelectDlg too trusting of column header namesGuest3closed23.2
1005TodoSkylineAdd support for setting Settings > Integrate All from the command-lineGuest2closed23.2
1004TodoSkylineAdd support for adding modifications from the command-lineGuest2closed23.2
1003DefectSkylineFix TransitionGroup.GetTransitions() for small molecules to use library information when availableGuest3closed23.2
1002DefectSkylinetrouble with transition list created with our own document grid exportGuest3closed 
1001DefectSkylineneed exceptiion handling for bad MoleculeMassOffset.SplitFormulaAndMasses inputGuest3closed 
1000DefectSkylineWhen reading peptide transition lists we should offer to apply document settings - adding reporter ions, other precursor charges etc.Guest3closed 
999DefectSkylineInvestigate using ExcludeFromAssay field from DIA-NNGuest3closed 
998DefectSkylineFix issues with matching DIANN speclib to report TSVGuest3closed 
997DefectSkylineWe should allow adducts with formulaic losses on mass-only molecule description (e.g. don't complain that Adduct "[M-CO2]-" calls for removing more C atoms than are found in the molecule [+331.977251])Guest3closed 
996TodoSkylineFeature detection could be reworked to parallelize tasksGuest3closed 
995TodoSkylineImport Peptide Search should default to no decoys when Library.UseExplicitPeakBounds will be usedGuest3closed23.2
994TodoSkylineFile > Import > Peptide Search - FASTA page should have Peptide Settings - Filter optionsGuest3closed23.2
993DefectSkylineWeirdness in the raw data view when switching from IM-containing replicate to non-IM replicateGuest3closed23.2
992DefectSkylineDIA-NN Speclib handling in BlibBuild mishandles n-terminal modsGuest2closed23.2
991DefectSkylineWe should add a "Run" submenu to Skyline's File menu, and move Feature Detection, Encyclopedia, and peptide search engines there from the "Import" menuGuest3closed 
990TodoSkylineClean up Transition Settings and IMS arguments in command-line documentationGuest3closed23.2
989TodoSkylineNeed to add new coverage for Peptide Settings changes by command-lineGuest1closed23.2
988DefectSkylineNeed to normalize Transition Settings change command-line outputGuest3closed23.2
987DefectSkylineDisplaying tooltip for protein sometimes takes a really long time when "Enforce Uniqueness" is enabledGuest3closed 
986DefectSkylineMake ion mobility library editor searchableGuest3closed 
985DefectSkylineTarget tree's Find function results window says "Peptide" where it should say "Molecule"Guest3closed 
984DefectSkyline"zombie chromatograms" complicate merging of Skyline filesGuest3closed 
983DefectSkylinemanually modifying molecule mass does not modify the m/z of precursor transitions belowGuest3closed 
982TodoSkylineImproved error message when user tries to File>Open a mass spec data file in SkylineGuest3closed 
981DefectSkylineCE optimization does not work for SCIEX QTOF instrumentsGuest3closed 
979DefectSkylineSupport isotope nomenclature like "[13C]3H7[15N]O2" (that's C'3H7N'O2 in Skyline-speak)Guest3closed 
978DefectSkylineNeed a way to represent targets that were dimers in the IMS stage but broke into monomers in the MS stageGuest3closed 
977DefectSkylineNeed a way to import and display keys other than InChI, SMILES, KEGG etc - e.g. "METLIN ID"Guest3closed 
976DefectSkylineLibrary Explorer: Allow for searching within peptide/molecule descriptionGuest3closed 
975TodoSkylinefeature request: User-editable keyboard shortcuts for menu itemsGuest3closed 
974DefectSkylineOpenDataSourceDialog WIFF/WIFF2 data type causes file selection to be painfulGuest2closed23.2
973TodoSkylineAdd a way to add annotation definitions to a Skyline document from the command-lineGuest2closed23.2
972DefectSkylineFeature: Export mProphet features from commandlineGuest3closed 
971DefectSkylineSmall molecule transition list reader could be more clever about setting formulasGuest3closed 
970TodoSkylineFeature request: Right click on molecule in the molecule tree to “Add to iRT Database”Guest3closed 
969DefectSkylineTrouble handling transition lists that declare precursor isotopesGuest3closed 
968DefectSkylineNullReferenceException when uploading to a saved Panorama URIGuest3closed 
967DefectSkylineCreate matching small molecule versions of all standard peptide reports in Document GridGuest3closed 
966TodoSkyline"Mobiligram" display for ion mobility filtered chromatograms (alternate view to our ion mobility heatmap)Guest3closed 
965TodoSkylineAdd command arg to SkylineRunner.exe to run any instance of Skyline by pathGuest3closed23.2
964DefectSkylineFeature Request - Surrogate calibration curvesGuest3closed 
963DefectSkylineFeature Request - Remove Replicate/Result from Chromatogram or Replicate Right-click menuGuest3closed 
962DefectSkylineFind CCS values for targets not found in an IMSDB library without changing existing valuesGuest3closed 
961TodoSkylineShow units for pressure traces in Skyline chromatograms and enable Panorama to do the sameGuest3closed23.2
960DefectSkylineChinese language update: "Centroided" in the drop down list can be translated as 中心对称的Guest2closed23.1
959TodoSkylineImprove error message for BlibBuild failuresGuest2closed23.1
958DefectSkylineadd the Skyline version to the "More Info" text in alert dialogsGuest3closed