MS optimization for small molecules

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MS optimization for small molecules 120887548  2018-06-06 17:43
 

Hi there

I used to use skyline for peptide optimization, it is very useful. I recently start targeted analysis for small molecules. I am wondering if I also can use skyline for their MS parameters optimization such as CE, DP, CXP and etc. Which MS instrument is supported for that ?

Many thanks in advance!

 
 
Brian Pratt responded:  2018-06-07 08:33
Yes, the same optimization capabilities are available for small molecules. An excellent example can be found in the Small Molecules section of our tutorials page at https://skyline.ms/wiki/home/software/Skyline/page.view?name=tutorials .

Brian