Avant-garde for large DIA dataset

AvantGardeDIA
Avant-garde for large DIA dataset voellmy  2020-04-06
 

Hi,

I've been wanting to run Avant-garde on a large DIA dataset. The tool works successfully for me on a smaller dataset however when the number of files increases, the step where a csv is exported from Skyline (only to then re-import it) is either taking a very long time, or just crashes. I've been hoping to find a way to run the tool circumventing the steps run in Skyline, but unfortunately have not been able to find sufficient information online to do so. I'd appreciate if I could help some help to get this started.

Best,
Franziska