Dear Skyline Technical Support Team:
      First and foremost, I would like to express my sincere gratitude for developing such an indispensable tool for PRM proteomics data analysis. As a long-time user, Skyline has been instrumental in advancing my targeted proteomics research.
      I am writing to seek your expertise regarding two technical challenges I recently encountered:
     1. High-Resolution Chromatogram Export
     When exporting chromatogram images via the current interface (right click single sample's chromatogram > Save Image As), the resolution (approximately 300 dpi) falls short of the quality required for publication figures. While manual screenshot capture can improve clarity, this approach becomes impractical when processing multiple samples. Could you kindly advise if there is an undocumented high-resolution export option or whether such a feature might be considered in future updates?
     2. Bulk Export of Raw Chromatogram Data
     For experiments involving numerous peptides/samples, the current workflow of exporting raw chromatogram data (via Copy Chromatogram Data for individual entries) remains time-intensive. I attempted to extract raw retention times and intensities through customized reports (File > Export > Report), but the exported data failed to reconstruct chromatograms matching the quality displayed in Skyline. Is there an existing workaround for bulk export of raw chromatogram data, or could this functionality potentially be automated via the scripting interface?
     Given your team’s deep understanding of user workflows, any guidance on these matters—or insights into potential solutions under development—would greatly enhance my research efficiency. I am happy to provide additional context or testing datasets if needed.
     Thank you for your time and continued support. Looking forward to your guidance.

Best regards,
Meifeng
Wuhan spec-ally company
2025.04.09