Individual Regression Options for Peptides/Precursors | sascha | 2022-02-10 08:34 | |||||||||||||||||||||||||||||||||||
Currently, you can define regression options for the document in "Settings > Molecule Settings > Quantification" that apply for all targets. However, the response of individual targets is not the same, thus you might need for example a linear regression without weighting for molecule 1 and a quadratic regression with a 1/x weighting for molecule 2, and so on. After the last Skyline MS Online event, I was told that this is currently not possible in Skyline, and encouraged to report a feature request. It was suggested that these settings might be implemented in the document settings as "Explicit" molecule option. Since I do not have permission to open a new issue, I use this forum for this request. If this request needs any more clarification, please let me know. I would be grateful for the implementation of this feature, since it is the only obstacle to replace commercial quantification software in our lab. |
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