Exporting methods support for Excedion Pro Orbitrap

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Exporting methods support for Excedion Pro Orbitrap gschultz  2026-03-30 08:12
 

I am getting an error when attempting to export a method for the Excedion Pro. File>Export>Method. Can you add the Excedion Pro to the Instrument type?

 
 
Brian Pratt responded:  2026-03-30 10:03

Can you provide more information about the version of Skyline you're using, and the error you're seeing? Screenshots are great.

Thanks,
Brian Pratt

 
gschultz responded:  2026-03-30 10:18

Skyline-daily (64-bit) 26.1.1.083 (019490f698)

System.IO.IOException: The installed Thermo instrument type 'OrbitrapExcedionPro' does not match the requested output method type 'OrbitrapExploris480'. ---> System.IO.IOException: The installed Thermo instrument type 'OrbitrapExcedionPro' does not match the requested output method type 'OrbitrapExploris480'.
at pwiz.Skyline.Model.ThermoMassListExporter.EnsureLibraries(String expectedInstrumentType) in C:\proj\daily\pwiz_tools\Skyline\Model\Export.cs:line 1366
at pwiz.Skyline.Model.ThermoSureQuantMethodExporter.ExportMethod(String fileName, String templateName, IProgressMonitor progressMonitor) in C:\proj\daily\pwiz_tools\Skyline\Model\Export.cs:line 2287
at pwiz.Skyline.Controls.LongWaitDlg.RunWork(Action1 performWork) in C:\proj\daily\pwiz_tools\Skyline\Controls\LongWaitDlg.cs:line 263 --- End of inner exception stack trace --- at pwiz.Skyline.Util.ExceptionUtil.WrapAndThrowException(Exception x) in C:\proj\daily\pwiz_tools\Skyline\Util\Util.cs:line 1737 at pwiz.Skyline.Controls.LongWaitDlg.PerformWork(Control parent, Int32 delayMillis, Action1 performWork) in C:\proj\daily\pwiz_tools\Skyline\Controls\LongWaitDlg.cs:line 204
at pwiz.Skyline.Controls.LongWaitDlg.PerformWork(Control parent, Int32 delayMillis, Action1 performWork) in C:\proj\daily\pwiz_tools\Skyline\Controls\LongWaitDlg.cs:line 140 at pwiz.Skyline.FileUI.ExportDlgProperties.PerformLongExport(Action1 performExport) in C:\proj\daily\pwiz_tools\Skyline\FileUI\ExportMethodDlg.cs:line 2805

 
Brendan MacLean responded:  2026-03-31 06:21

I have merged a fix for this into the project. So, it will be in the next Skyline-daily and our patch release for Skyline 26.1 later this month. When you get it, you will want to choose just "Thermo" for the instrument type. I did considerable work last year to make auto-detection of Thermo instruments work, but each name does need to be assigned to a type of instrument. Clearly, you tried to help Skyline by choosing Exploris as the closest thing in the list. Unfortunately, I didn't go that far in the new implementation, i.e. here is an unknown type, treat it like this known type.

Hopefully, less than a week turnaround is good enough. Skyline-daily coming soon. Thanks for reporting it!

--Brendan