Ph.D., received a Ph.D. in analytical chemistry at the University of Florida, and completed a postdoc at the University of Pittsburgh’s Hillman Cancer Center. Susan is currently the executive director of the MS Core Facility at the Barnett Institute at Northeastern University, and a visiting scientist in the Proteomics Platform at the Broad Institute of MIT and Harvard. Susan’s research focuses on the development of experiments to measure potential protein biomarkers in cell lines and blood for diseases such as cancer. Susan has co-chaired a committee that is part of the National Cancer Institute’s Clinical Proteomic Technology Assessment for Cancer (CPTAC).
Ten years ago a group of about 20 dedicated triple quadrupole operators met at the Broad Institute to learn about the features of Skyline -- this modest beginning evolved into the Skyline User Group Meeting -- the reason you are here today. Nowadays, the Skyline user base has grown significantly with 94,000 new installations of Skyline since 2009. Birgit and I will provide an entertaining retrospective over the last 10 years – what were its key achievements?
How did Skyline bring results from labs together even when they used different instrumentation? By keeping its format, vendor-neutral, Skyline has developed great support from all the instrument vendors. In the initial days, we used Skyline for SRM supporting CPTAC projects, system suitability and biomarker research. Over time, the development team added new scan-type capabilities, such as MS1-Filtering, PRM and DIA and now even support for small molecule workflows! Great new features were implemented including iRT (indexed retention time), tool store connections and even linking Skyline with Panorama – the online repository for Skyline research data! A truly comprehensive quantitative environment for everybody, everywhere in the world!