Issue 513: Fix ExclusionUseDIAWindow setting to consider IsolationWindow.MethodStart and MethodEnd

issues
Status:closed
Assigned To:Guest
Type:Defect
Area:Skyline
Priority:3
Milestone: 
Opened:2017-05-04 by Brendan MacLean
Changed:2018-10-16 by Brendan MacLean
Resolved:2018-10-16 by Brendan MacLean
Resolution:Won't Fix
Closed:2018-10-16 by Brendan MacLean
2017-05-04 Brendan MacLean
Title»Fix ExclusionUseDIAWindow setting to consider IsolationWindow.MethodStart and MethodEnd
Assigned To»Brendan MacLean
Type»Defect
Area»Skyline
Priority»3
It appears that the option for excluding DIA windows from consideration for fragment ion extraction uses only the extraction window and not the measured window as the exclusion. While only the extraction window is considered valid for quantification, the entire measured window may contribute ions to the resulting spectrum. So, it would be more appropriate to exclude all of it.

Sadly, this may require some complicated backward compatibility to support now that it has been the way it is for so long.

2018-10-16 Brendan MacLean
resolve as Won't Fix
Statusopen»resolved
Seems unlikely to make the implementation list any time soon.

2018-10-16 Brendan MacLean
close
Statusresolved»closed
Assigned ToBrendan MacLean»Guest