Can Skyline calculate CCS error between Explicit and IM Library CCS values?

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Can Skyline calculate CCS error between Explicit and IM Library CCS values? Stelios Papazoglou  2025-06-12 03:09
 

Good morning Skyline team,

I'm working with ion mobility data from different IMS instruments and would like to know if it's currently possible to calculate CCS error directly within the software by comparing:

  1. Explicit CCS values (reference values entered manually), and
  2. Ion Mobility Library CCS values (experimental, obtained using the “Use Results” )

Is this currently supported in Skyline?
If not, is there any workaround within Skyline to achieve this kind of calculation?

This feature would be very useful for validating CCS accuracy and monitoring shifts during IMS data analysis and especially when comparing CCS values across different instruments.

Thanks you for your help!
Stelios