Drift Time Window Integration | asolosky | 2024-10-22 10:29 | |||||||||||||||||||||||
Hello, my name is Amie and I taught the Ion Mobility filtering for lipids tutorial during the last online Skyline course (last week). During the tutorial, we discussed how it would be helpful to be able to change the integration bounds within the drift time dimension, similar to how we are able to with chromatograms. Is this possible? Normally, we get around this by changing the resolving power window in the ion mobility transition settings, but sometimes there are peaks that fall outside the horizontal violet box that we would like to be able to include in our integrations (i.e., conformers), but only for certain targets, so I wouldn't want to change the filtering for the whole document. That is why I think being able to integrate within the drift time window just like we do for LC would also be super beneficial. I've included an example data file where this would be helpful. The retention time of interest is 9.6 mins, but at this retention time and m/z there are multiple peaks in the drift window. I would like to be able to integrate the first two peaks at drift times 23.56 and 25.36 ms (summed), but not the peak at 33.96 ms. Can you make this possible in Skyline? Thanks in advance for taking a look at this! |
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