TQ-XS Data not loadable in Skyline-daily (64-bit) (b5b0d400b)

TQ-XS Data not loadable in Skyline-daily (64-bit) (b5b0d400b) Marvin  2024-04-04 00:14

Dear all,
As I tried to load my measured data into skyline, the error:

  • are just spaces for intern names without special characters.

At 09:08:
Failed importing results file 'C:\Users***\MS24-0188_AltDB_074.raw'.
[pwiz::CLI::msdata::ReaderList::read] Unhandled exception: Generic Error
pwiz.Skyline.Model.Results.ChromCacheBuildException: Failed importing results file 'C:\Users\mbr\Desktop\Neuer Ordner\MS24-0188_AltDB_074.raw'.
[pwiz::CLI::msdata::ReaderList::read] Unhandled exception: Generic Error ---> System.Exception: [pwiz::CLI::msdata::ReaderList::read] Unhandled exception: Generic Error
bei pwiz.CLI.msdata.ReaderList.read(String filename, MSData result, Int32 runIndex, ReaderConfig config)
bei pwiz.ProteowizardWrapper.MsDataFileImpl..ctor(String path, Int32 sampleIndex, LockMassParameters lockmassParameters, Boolean simAsSpectra, Boolean srmAsSpectra, Boolean acceptZeroLengthSpectra, Boolean requireVendorCentroidedMS1, Boolean requireVendorCentroidedMS2, Boolean ignoreZeroIntensityPoints, Int32 preferOnlyMsLevel, Boolean combineIonMobilitySpectra, Boolean trimNativeId) in C:\proj\pwiz\pwiz_tools\Shared\ProteowizardWrapper\MsDataFileImpl.cs:Zeile 200.
bei pwiz.Skyline.Model.Results.MsDataFilePath.OpenMsDataFile(Boolean simAsSpectra, Boolean preferOnlyMs1, Boolean centroidMs1, Boolean centroidMs2, Boolean ignoreZeroIntensityPoints) in C:\proj\pwiz\pwiz_tools\Skyline\Model\Results\MsDataFilePath.cs:Zeile 295.
bei pwiz.Skyline.Model.Results.ChromCacheBuilder.BuildCache() in C:\proj\pwiz\pwiz_tools\Skyline\Model\Results\ChromCacheBuilder.cs:Zeile 191.
--- Ende der internen Ausnahmestapelüberwachung ---


Do you have any suggestions how to tackle this problem?

We tried an older version of skyline, but still couldn´t open some of the files...

Best wishes,

Matt Chambers responded:  2024-04-04 11:19

Hi Marvin,

I think is an error trying to read analog channels, a feature which was added recently. I've got error handling implemented locally (to skip the channels with a warning message) but it's not committed yet and will take some time to make it into a Skyline-daily even when it is. So in the meantime I think you can skip those channels by moving the CHRO*.* files to a subdir in your .raw folder. Let me know if that doesn't work and I'll dig deeper.

Marvin responded:  2024-04-05 00:11

Hey Matt,

I tried to switch several subfolders on my PC, but not on the XS.
In the latest version of non-daily Skyline, the import works fine and I´m using that version till the problem is fixed.

Thanks for your reply! Looking forward to the implementation!

Best wishes

Matt Chambers responded:  2024-04-05 08:43
Sorry I wasn't clear. You need to move files around inside your .raw directories, not move the .raw directories around. For example, go from: