I don't think there is any way to do what you want to do in Skyline but if you send us your Skyline document we might be able to figure something out.
In Skyline you can use the menu item:
File > Share
to create a .zip file containing your Skyline document and supporting files including extracted chromatograms.
If that .zip file is less than 50MB you can attach it to this support request. You can upload larger files here:
It sounds like what you would like to be able to do in Skyline is just tell Skyline what the slope and intercept of the calibration curve for a particular molecule is. You would just copy those numbers from the calibration curve that you have. Unfortunately, Skyline does not have any feature like that, so you would probably have to be doing this sort of calculation in some other program such as Microsoft Excel.