Hi Mehar,
It may be that a Thermo Fusion isolation list will work for the Thermo Eclipse. If not, can you detail for us the differences between what you get and what you need?
Otherwise, you may need to use File > Export > Method where we just enabled method export for the Thermo Eclipse. You need to provide a template method file, but then Skyline will add the precursors for your PRM to that template. Often this is preferable to exporting the isolation list and then importing it into a template method manually.
Hope this helps. Thanks for posting to the Skyline support board.
--Brendan