|Addition of a deamination modification on an N-ter cysteine||laurie josset||2022-09-30|
Hello to all,
I am working on the quantification of desmopressin, when I add the peptide sequence in skyline I end up with arginine vasopressin (that is normal). I tried to manually create the deamination modification to apply on the N-ter cysteine, only I don't end up with the right m/z for the precursors (I want 535.35 ++ and Skyline predicts me 545.7196 ++). For the chemical formula I indicated "O-HC", maybe this is not correct. Would it be possible to help me?
Thanks in advance,
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