Peak symmetry, asymmetry or tailing factor

Peak symmetry, asymmetry or tailing factor o heravizadeh  2022-09-25 19:53


Is there any way to have the information regarding peak asymmetry, symmetry, or tailing factor in the "Document grid" table?
I currently tried to use the SProCop_1.3 tool, However, it gives me a bunch of errors and the result is not clearly reported in a table format for all the compounds' peaks.
As the mentioned parameters are important for peak quality assessment and I am not interested to use two separate software for analyzing my data, I hope somebody can help me regarding this matter.

Thank you so much,

Nick Shulman responded:  2022-09-25 20:16
Instead of using "SProCop", we recommend that you use "AutoQC".

I am supposed to implement skewness and kurtosis in the next version of Skyline.
There are some screenshots showing what the feature will look like here:

Are you saying that you have another tool which tells you the asymmetry and tailing factors for your data?
It would be helpful if you could send me your Skyline document as well as the numbers that you got from the other tool so that I can make sure that the numbers that Skyline will calculate will be correct.

In Skyline you can use the menu item:
File > Share
to create a .zip file containing your Skyline document and supporting files including extracted chromatograms.
If that .zip file is less than 50MB you can attach it to this support request. You can upload larger files here:

-- Nick
o heravizadeh responded:  2022-09-25 21:57
Hello again,

Thank you so much for your reply. I will try "AutoQC" to see how it works.
Adding skewness and kurtosis to the next Skyline version would be also very helpful as I can use these parameters instead of the tailing factor.
The Shimadzu "LabSolutions" software is able to report the tailing factor and peak width at different heights during the peak picking process. I will prepare this information for some compounds' peaks and share it with you soon.

Best regards,