|I wonder if Skyline will join MS-based RNomic and DNomic studies?||licky lck||2022-07-18|
Dear Skyline team,
I really appreciate the massive contribution of Skyline to the proteomics community, and it is one of the most important software I used during all of my proteomic studies. Recently, researchers from epigenetics, biology and pharmacy are trying to "borrow" the bottom-up concept from proteomics to study modifications in oligonucleotides (from DNA and RNA) using MS-based methods. So I wonder if the Skyline team would consider joining the party?
I have been using Skyline to study site-specific protein modifications on peptides using the manual peptide insert function, and it would be absolutely a game changer if a similar function is available for nucleotide study in Skyline for epigenetics-related studies as there is still a blank in the study of DNA (or RNA) modifications site-specifically. I will be working in this field in the coming years, and I would love to hear if Skyline is also interested in working with DNA and/or RNA. Thank you very much for your time and patience.