|computer resource configuration||bobxiong||2022-07-12|
Hi Skyline Team,
I have an odd question about computer configuration in support of Skyline usage. I tested a manually prepared transition list of 4000 transitions on a 3G mzML DDA data file using the Molecule interface. While importing the transition list and the result mzML data seemed slow, it was not responding to any kind of clicking to view the data afterwards. The computer hung up. Please see the attached for my current computer properties.
Assume that I have generous funding, what kind of computer resource configuration should I go for? I do not want to be bottlenecked by a computer to perform Skyline work. For a disulfide linked tri-peptide molecule, the transition list can easily reach 50K transitions to consider a combination of multiply charged precursor and product ions. I expect it to become even more demonding if multiple replicates of mzML data are loaded in Skyline.
I would greatly appreciate any suggestion/recommendation.
Thanks a lot,
Bob Xiong, Ph.D.