|Skyline Tuning optimisation vs instrument software Tuning optimisation Shimadzu 8060?||jxg918||2022-06-27|
Does anyone have any experience comparing an instrument-automatic optimisation process to select the best voltage settings vs Skyline's CE optimisation? Does Skyline also optimise other voltage settings (such as interface voltage, DL bias, Qarray RF, Q1 and Q3 pre-rod bias)?
I've been using skyline for a proteomics project to quantify very-low abundant proteins in very rare samples.. So I'd need to have my instrument settings as optimal as can be. Just don't know if it's best to use Skyline or the vendor-specific optimisation tool.
If anyone with experience on a Shimadzu 8060 could help me with this, would be much appreciated!