Error when inserting cross-linked peptides into document

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Error when inserting cross-linked peptides into document Juan C. Rojas E.  2022-06-09 11:29
 

Hi Skyline team,

So I am trying to insert a set of cross-linked peptides into Skyline through Edit -> Insert -> Peptides... by copying a list of crosslinked peptides that I parsed from a MeroX output into Skyline format. I loaded a .txt file (attached) with these sequences in Excel and attempted to copy-paste the whole list into the window in Skyline as I usually do for other "normal" peptides, but keep getting a "This peptide sequence contains invalid characters".

Strangely, when I click inside the cell of "Peptide Sequence" and paste a single sequence from the parsed list it accepts the entry. Any ideas what is going on?

Attached is also the Skyline document with the required mods and some pre-loaded peptides.

Hope ASMS was fun!
Sincerely,
Juan C.