Wishlist: Indicator for transitions that are diagnostic of PTMs

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Wishlist: Indicator for transitions that are diagnostic of PTMs dkueltz  2022-01-02
 

Hi Nick, Brendan et al.,

Wishlist item: It would be nice to have an identifier for transitions that are diagnostic of fragment ions containing a specific PTM, i.e. some sort of flag or column that can be sorted and filtered in the document view grids and indicates those transitions that are diagnostic for a PTM (i.e. all y ions greater than the position of the PTM in question from the c terminus and all b ions greater than the position of the PTM in question from the N terminus, etc.). Having such an identifier would help a lot in automating the process of finding diagnostic transitions for PTMs and save a lot of time by not having to do this manually. Perhaps there is already a way to do this and I am just missing it.

Thanks for considering this wishlist request,
Dietmar

 
 
Nick Shulman responded:  2022-01-18
Dietmar,

Can you send us an example Skyline document where you would want this extra information displayed?
We have a new employee in the lab who is working on this feature and it would be helpful to have an example document to start with.
-- Nick
 
dkueltz responded:  2022-01-19
Hi Nick,
That's great that you are planning to find a way for implementing this functionality! Yes, of course, I will upload a document within the next few days and annotate some specific peptides to point out the possible scenarios. I will let you after uploading is complete.
Thanks!
Dietmar