Chromatogram Information Unavailable - The document must be fully loaded before it can be saved to a new name.

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Chromatogram Information Unavailable - The document must be fully loaded before it can be saved to a new name. leaptrkl  2021-10-22
 

Hello and thanks in advance for your help!

I was working in Skyline daily with one document (no issues) and tried to open another, but none of the chromatograms would load in the second document. I closed both documents (saving the first before closing), and now neither will show chromatograms. I tried saving the document as a new name (received message "The document must be fully loaded before it can be saved to a new name.") , waiting 10 minutes for the file to load (nothing appeared to be happening), tried re-importing the files (received message "All results must be completely imported before any can be re-imported."), and tried re-scoring in place (received message "All results must be completely imported before they can be re-scored."). I closed and opened the file 5 times, since another someone with this issue in another support thread said the issue resolved after 3 attempts.

The software still shows my retention times, mass errors, calibration curve, etc., but no chromatograms. I tried exiting out of all the chromatograms and then bringing them back up with View>Arrange Graphs but that didn't do it either.

I was able to see chromatograms for an unrelated Skyline document I created a few months ago during a Skyline Online Course, but I tried to open my document of issue afterwards and still no chromatograms.

 
 
leaptrkl responded:  2021-10-22

Update

I found under Transition Settings > Ion Mobility that I had an Ion Mobility Library. Since libraries not loading was suggested as the cause for another similar issue on the forum, I tried removing the library. The chromatograms loaded right away. I reselected the library and the chromatograms stayed. Should I be aware of any related issue that might not be apparent? Like is the library likely corrupted, or is it being used at all?

Thank you!