Can we gave multiple modification on one amino acid

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Can we gave multiple modification on one amino acid Bo An  2021-09-22
 

I have a peptide started with K on the n-terminal, when biotinylated the peptide, this n-terminal K will be double labled with biotin, is there a way we can put multiple modification on the same amino acid like this situation? Thanks.

 
 
Nick Shulman responded:  2021-09-22
Skyline typically only allows you to put one modification on any particular amino acids.
If you need to put two modifications on the same amino acid, we recommend that you define a single modification which is the combination of the two modifications.
-- Nick