FAIMS PRM maria hernandez-valladares  2021-04-15

Hi there,
just to be sure, can we analyze FAIMS PRM data directly in Skyline or do we have to work with split CV-raw files?

Many thanks

Brian Pratt responded:  2021-04-15

You can associate each precursor with a CV value and Skyline will use that in chromatogram extraction - no need to split your files.

There are several ways to do this -
as part of a spectral library,
as part of your transition list import,
by building an ion mobility library from inspection of the raw data,
or by entering values in the Document Grid.

Thanks for using the Skyline support board!

Brian Pratt

maria hernandez-valladares responded:  2021-04-20

thanks a lot Brian!