We may have gotten confused by the mention of "optimization" in your request, which Kaipo is working on. However, the Thermo full-scan instruments (Orbitrap, ion trap) use normalized collision energy (NCE) and therefore usually do not require an equation for CE. They have their own equations embedded in the instrument software. This allows Skyline to mostly use a single NCE value for all peptides in a given method.
There may be ways to change this, but I am not entirely sure. There definitely will be once Kaipo's work is completed. Then it will be possible to perform CE optimization for PRM as we have described for SRM (see the CE Optimization tutorial - https://skyline.ms/tutorial_optimize_ce.url, and MacLean, Anal. Chem. 2010). Though, I am not clear that this is what you are seeking.
So, very short answer, for a Fusion Lumos, you generally do not need to worry about the CE setting in the Transition Settings - Prediction tab.
If you truly want to pursue optimized NCE values on a Lumos, let us know and we would be interested in having your feedback on that project currently underway.