|NIST library with Unimod, but untypical modifications||solis||2020-11-26|
Dear Skyline team,
thanks for your continuous improvement of the software and the tools within it.
I have an issue with Skyline recognizing "Propionyl" modifications in a NIST library as well as Methy and Propionyl modifications co-occurring on the same site. As you may know, these PTMs are relevant in the context of some protocols for histone PTM analyses. Could you please let me know if indeed this is a current limitation of Skyline or if something is wrong with my attached NIST library instead?
And if the former is the issue, you could then maybe make Skyline able to recognize any modification as long as its name is in the Skyline Modifications list.
Thank you very much and my best regards.