|Import of Mascot error tolerant searches in Skyline||ingo.wohlgemuth||2020-07-02|
Hey Skyline team,
I try to import error tolerant Mascot searches with a focus on amino acid substitutions. While many PTMs can be imported, amino acid substitutions which were found in Mascot are often lost in Skyline (e.g L to V mutations, see picture). Is the a rational for that? How Sykline handles cases is which the delta mass could not unambiguously assigned (e.g: D to E substitution vs D methylation) when both interpretations are available in Mascot?
Thanx a lot!