Selection of peptides based on the dot product

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Selection of peptides based on the dot product sunbergsoon  2019-03-09
 

Hi,

After applying the library on the Skyline, we found that you also calculate the dot product for each peptide.
Actually, we want to do high-quality searching and only keep the good result, so can I select the searching
results based on the dot product? For example, filtering the peptides with dot product less than 0.8.

Thank you very much!

Best regards,
Sunberg

 
 
Brendan MacLean responded:  2019-03-09

Hi Sunberg,
Yes, you can do that with the Edit > Refine > Advanced - Results tab (now Refine > Advanced in Skyline-daily). The Targeted Method Editing tutorial actually goes over this:

https://skyline.ms/tutorial_method_edit.url

You can learn a lot from the tutorials and webinars. Good luck with your data processing. Thanks for using Skyline.

--Brendan

 
sunbergsoon responded:  2019-03-09

Hi Brendan,

Thanks a lot for your kind guidance and help, I really appreciate it.

Thank you so much!

With my best regards,
Sunberg