Strange error message during import of 6490 data

Strange error message during import of 6490 data tasso miliotis  2018-11-07

I can import QQQ data acquired with one of our 6490 instrument that is using Masshunter version B.06.00.
However, I can not import QQQ data acquired with another 6490 instrument that happens to have the MassHunter
version B.08.00. The data are in both cases located on the local harddrive. I am using the same Skyline document
and the same acquisition method. I obtain the error message when trying to load data generated from the
B.08.00 instrument. Any ideas to why I obtain the error message below?

At 15:46:
Failed importing results file 'C:\Users\farmtm\Desktop\DATA_Skyline\Plate1_1_38+3HVs_RIA6490\181103_tmi_QC-A_Repl_1.d'.
[MassHunterDataImpl::ctor()] File not found: C:\Users\farmtm\Desktop\DATA_Skyline\Plate1_1_38+3HVs_RIA6490\181103_tmi_QC-A_Repl_1.d\AcqData\MSScan.xsd

Inner exceptions:
Exception type: System.Exception
Error message: [MassHunterDataImpl::ctor()] File not found: C:\Users\farmtm\Desktop\DATA_Skyline\Plate1_1_38+3HVs_RIA6490\181103_tmi_QC-A_Repl_1.d\AcqData\MSScan.xsd
[MassHunterDataImpl::ctor()] File not found: C:\Users\farmtm\Desktop\DATA_Skyline\Plate1_1_38+3HVs_RIA6490\181103_tmi_QC-A_Repl_1.d\AcqData\MSScan.xsd
at filename, MSData result, Int32 runIndex, ReaderConfig config)
at pwiz.ProteowizardWrapper.MsDataFileImpl..ctor(String path, Int32 sampleIndex, LockMassParameters lockmassParameters, Boolean simAsSpectra, Boolean srmAsSpectra, Boolean acceptZeroLengthSpectra, Boolean requireVendorCentroidedMS1, Boolean requireVendorCentroidedMS2, Boolean ignoreZeroIntensityPoints, Int32 preferOnlyMsLevel) in C:\proj\skyline_4_2_x64\pwiz_tools\Shared\ProteowizardWrapper\MsDataFileImpl.cs:line 142
at pwiz.Skyline.Model.Results.MsDataFilePath.OpenMsDataFile(Boolean simAsSpectra, Int32 preferOnlyMsLevel) in C:\proj\skyline_4_2_x64\pwiz_tools\Skyline\Model\Results\MsDataFilePath.cs:line 272
at pwiz.Skyline.Model.Results.ChromCacheBuilder.BuildCache() in C:\proj\skyline_4_2_x64\pwiz_tools\Skyline\Model\Results\ChromCacheBuilder.cs:line 191

Brian Pratt responded:  2018-11-07
It sounds like the directory was incompletely copied (.d "files" are really directories with lots of individual files in them). Are you able to open this with any other software?

Thanks for using the Skyline support board!

Brian Pratt
tasso miliotis responded:  2018-11-07
Hi Brian,
yes you are right. When I compared the file structure of the copied data file against the original data file,
one important file (“MSScan.xsd”) was missing in the copied data file...
For some strange reason when I copy the data files over the network I observe this issue. I solved the issue
by copying the data files from the acquisition computer to a local USB drive and then back to my Skyline PC.
That way I copied the entire data file structure. Thanks for the incredible fast response time, which is very much