Dear Skyline team,

Apologies for the somewhat silly request but we have been sent raw files for analysis a number of times by people who insist on using the micro symbol in the file names (e.g. to specify the concentration or mass of protein in the sample or volume injected into the MS). This appears to create issues for Skyline, i.e. DDA files can't be imported via Import -> peptide search. We are also currently experiencing difficulties with DIA files with the micro symbol in the name; which import okay but peak quantification appears to fail; although we are yet to really demonstrate that this issue is caused by the 'micro' character. Simply renaming the files is not sufficient; it appears that raw files 'know' what they were originally called. We are looking into possible ways around this and would appreciate any suggestions if you already have some, such as converting the raw file to a file format we can possibly view and edit; but I thought I would raise this as a possible request as others might run into the same issue.

Obviously this is just poor file naming practice but once created, it does not appear to be trivial to correct.

Many thanks,

Tim