Error Loading Data Files

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Error Loading Data Files Kendra Adams  2018-08-07 06:47
 

Hi All,
I have been having an issue with my Skyline document, for some reason the data isn’t loading and I receive the attached error message upon opening the document with Skyline Daily 4.1.1.18179. It also tells me I cannot save the document under a new name because it is not “fully loaded”. The data that is imported into the document is on a server and I’m wondering if that is an issue, however, I’ve been using this data and document successfully for a month or two without any issues and it suddenly seems to have stopped working! I am working with a Waters TQ-S using a targeted small molecule method.
Thanks in advance!
Kendra

 
 
Nick Shulman responded:  2018-08-07 10:26
I believe the file "5055_SkylineMetDev_v1.skyd" is corrupted. Some bytes in the file must have gotten changed somehow.

One way to work around this problem would be to delete the file and then open your .sky file.
When Skyline notices that the .skyd file is missing, Skyline will try to extract the chromatograms from the raw files again. Skyline will be able to find those raw files if they are either in the same location as they were originally, or if they are in the same directory as the .sky file.