|Skyline external tool using SkylineTool not able to import small molecule blib from directory using AddSpectralLibrary command||Chris Ashwood||2020-11-13|
Hi Skyline Support Team,
I hope you are doing well.
I am currently trying to fix a new error that I have tried to fix with no avail. Has the new Skyline updates (daily or stable) changed how they handle external tool directories and paths? Or the SkylineTool?
The C# app I am developing loads small molecule spectral libraries using the SkylineTool with the following command:
Skyline appears to be unable to find the blib file (as shown in red in the attached image) despite the blib being in the tool directory. To my knowledge, this command has not caused any issues until I updated to the newest Skyline versions. I also get an error (shown below) that the document must be fully loaded so I cannot share the full Skyline document with the Share button.
I rolled back my daily version but it did not seem to fix the issue. And I also tried an older version of my program that worked fine and it also failed.
Any help would be appreciated because I'm going a little crazy trying to find what I changed on my end to cause this issue. I have included the Skyline assay and spectral libraries in the uploaded file (Skyline_SpecLib_error.zip).