Looking for IM information in large libraries introduces a perceptible lag - this needs to be done more efficiently. For the moment it is just disabled for peptides.


From an email thread 11/30/2021:

Brendan MacLean
Attachments
5:59 AM (6 hours ago)
to Skyline

I am sure this is related to Henry’s be work on lookups for the spectral library explorer which we may just want to disable for proteomics as the value seemed low. Extra indexes should be built on a background thread and not block viewing the library until a lookup type is chosen.

Gotta fix this for 21.2.

---------- Forwarded message ---------
From: Eduard Sabidó <eduard.sabido@crg.cat>
Date: Mon, Nov 29, 2021 at 11:54 PM
Subject: Re: Participant Page
To: Brendan MacLean <brendanx@proteinms.net>
CC: Cristina Chiva <cristina.chiva@upf.edu>


Dear Brendan,

I also noticed that when you select View/Spectral Libraries Skyline-daily v21.1.1.316 freezes for 30-60 sec when having a large library already built. This happens in tutorial 4 when analyzing DIA data, although maybe it is expected due to the size of the library.

Eduard

--
Eduard Sabidó, PhD
Head of the CRG/UPF Proteomics Unit

Centre for Genomic Regulation (CRG)
Carrer Dr. Aiguader 88
08003 Barcelona, Spain

Tel. +34 933 160 834
email: eduard.sabido@crg.eu

This got fixed, but regardless, Henry is no longer with us.