Following up on our email thread, we've had a request recently from Thermo to calculate additional values for each chromatogram peak to assess is asymmetry or skewness. At a high level, the intent is to assess how the observed peak differs from a Gaussian distribution. Once Skyline is calculating the values, we'll want to update Panorama to import it and likely make it available as a QC metric.
I am following up to get more details on reference calculations or other guidance. But if nothing else this issue can serve as a reminder to follow up again.
Here's a related request from 2019:
Also note that this is one of the attributes that SProCoP says it tracks: