Issue 600: Skyline-Daily Small molecules: Filter to screen out false positives based on number and proportion of transitions.

issues
Status:open
Assigned To:Brendan MacLean
Type:Defect
Area:Skyline
Priority:3
Milestone:4.2
Opened:2018-10-09 by ntharay
Changed:2018-10-09 by ntharay
Resolved:
Resolution:
Closed:
2018-10-09 ntharay
Title»Skyline-Daily Small molecules: Filter to screen out false positives based on number and proportion of transitions.
Assigned ToGuest»Brendan MacLean
Notify»ntharay
Type»Defect
Area»Skyline
Priority»3
Milestone»4.2
After using Skyline for a couple of months we have two issues which we are finding it difficult to resolve.

1) Is there a way to apply a filter so that a peak is positively identified only if it has all the required transitions from the transition list, that too in the right proportion?

2) At times the program picks up peaks with the right transitions even if they are way away the specified retention time window, which result in false positive hits.

 Thanks for this wonderful program.