Issue 333: Add "Exclude precursor isolation window" checkbox to Transition Settings - Filter

issues
Status:closed
Assigned To:Guest
Type:Todo
Area:Skyline
Priority:3
Milestone:2.6
Opened:2014-05-21 by Brendan MacLean
Changed:2014-07-19 by Brendan MacLean
Resolved:2014-07-19 by Brendan MacLean
Resolution:Fixed
Closed:2014-07-19 by Brendan MacLean
2014-05-21 Brendan MacLean
Title»Add "Exclude precursor isolation window" checkbox to Transition Settings - Filter
Assigned To»Brendan MacLean
Type»Todo
Area»Skyline
Priority»3
Milestone»2.6
In DIA methods it is often desirable to exclude product ions that fall within the m/z range of the precursor isolation window. That is, for a precursor 520.1234, which falls within the DIA window 500-525, if is desirable to exclude all product ions between 500-525 in the MS/MS scan on which product ion extraction is performed.

To enable this in the UI, we should remove from the Transition Settings - Filter tab, the field "Precursor m/z window", when the Full-Scan Acquisition method is DIA, and replace it with a checkbox "Exclude precursor isolation window" (only when an explicit isolation scheme is provided), which would have the effect described above. That is, when it is checked, for each precursor, all product ions that fall within the range(s) of the isolation windows that include it would be excluded from the targets list.

2014-07-19 Brendan MacLean
resolve as Fixed
Statusopen»resolved
Dario has committed code from Hannes for this.

2014-07-19 Brendan MacLean
close
Statusresolved»closed
Assigned ToBrendan MacLean»Guest