Can you give us more information about what error message, if any, you are seeing?
We always recommend running setup.exe as an ordinary user, not administrator. Skyline only ever gets installed for only the currently logged in user, I believe, regardless of how you run setup.exe.
If you do need to install Skyline for multiple users, you can use the Skyline administrator installer: https://skyline.ms/wiki/home/software/Skyline/page.view?name=install-administator-64
However, for most things, we recommend the regular install of Skyline, since that is the only variant that knows how to automatically check for updates.
Let us know what error you are seeing, and send us that log file if Windows shows it to you.