Shimadzu data file not loading egauth  2020-06-08 09:03
 

Hi!
I'm encoutering a problem when loading a specific MRM Shimadzu data file inside Skyline 20.1.0.76. The error is:

Failed importing results file 'E:\Shimadzu Joe\20200601002_Repro_Cocaine_Hexane_003.lcd'.
The sample 20200601002_Repro_Cocaine_Hexane_003 contains no usable data.

I attach the Skyline method as well as the problematic .lcd data file. I also included another data file from the same MS but with a different MS method that loads correctly with the same Skyline method.

Can someone spot where the problem is?
Thanks!

 
 
Brian Pratt responded:  2020-06-08 09:58

Thanks for the files. This is a Skyline bug - the problem file has a single chromatogram, and Skyline thinks that it must be metadata rather than an actual chromatogram. Any file with 3 or more chromatograms should load fine.

We will get this fixed for the next Skyline-Daily. Thanks for bringing it to our attention!

Best,

Brian Pratt

 
egauth responded:  2020-06-08 10:10

Great! I initially opened a github issue (https://github.com/ProteoWizard/pwiz/issues/1102), should I close it?

 
Brian Pratt responded:  2020-06-08 10:16

Yes, please do. Thanks!