Skyline results - background column

support
Skyline results - background column dspiciarich  2018-04-30 10:18
 
I'm running small molecule samples and I see a column with "Area" and one one with "Background" and wondering if you could explain what the background refers to? How is it calculated and how is it generally used?

For example (see attachment)

Thank you,
David
 
 
Nick Shulman responded:  2018-04-30 10:45
Skyline calculates background area by integrating under a horizontal line drawn between the start and end of the peak.

Here's a diagram explaining it:
https://skyline.ms/announcements/home/support/thread.view?rowId=2874