R&D Specialist - Analytical Chemistry

R&D Specialist - Analytical Chemistry diana saggese  2021-06-25

Our Analytical Chemistry Group of Regeneron Pharmaceuticals Inc. in Tarrytown, NY, is seeking a Research Specialist. In this role you will be working in a state-of-the-art mass spectrometry lab and developing top-down and bottom-up mass spectrometry analytical methods for therapeutic protein product analysis. You will focus on the biochemical characterization of therapeutic protein at all stages of development, developing LC/MS methods for protein primary structure analysis, disulfide linkage determination, carbohydrate profiling, protein variant structural determination and post-translational modifications. Furthermore, you will conduct analytical methods qualification for late stage drug development programs. The individual will also be involved in developing innovative mass spectrometry technologies to support Regeneron's upstream R&D programs.


•Develop LC-MS based analytical methods to support the development of monoclonal antibody-based therapeutic proteins;
•Execute a wide variety of LC-MS-based experiments on different instruments based on protocols provided in SOPs, literature, presentations, or by other scientists;
•Conduct analytical methods qualification to support the late-stage therapeutic protein development programs;
•Perform LC-MS data analysis using various software and bioinformatic tools to elucidate the quality attributes therapeutic protein candidates and/or products;
•Document experiments, results and findings in electronic laboratory notebook (ELN); presents work at the group and project meetings; participates in the writing of technical reports, SOPs, and analytical method protocols, etc.;
•Summarize results in a concise format (graphs, figures, tables, etc.) to support presentations, peer reviewed publications, regulatory documents, etc.;
•Participate in general lab and instrument maintenance


•You have strong initiative and seek to complete results-oriented tasks and learn new technologies related to Analytical Chemistry.
•You are capable of multi-tasking, working both independently and within a team culture.
This role requires a BS or MS in Chemistry, Biochemistry, or related field from an accredited university years post-graduate experiences (BS 5+yrs; MS 2+ yrs) in protein mass spectrometry. Knowledge and hand-on experience in LC-MS based protein, peptide and PTM analysis preferred. Good written and verbal communication skills and excellent interpersonal skills needed. Ability to learn new technologies and solve problems preferred. Enthusiasm in science with a motivation of making contributions in a team environment preferred.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

Check out this job:https://careers.regeneron.com/job/24397BR/R-D-Specialist-Analytical-Chemistry-1-of-2

Contact: diana.saggese@regeneron.com