|Scientist, Quantitative Proteomics - Denali Therapeutics, South San Francisco, Ca||auger||2020-12-17|
Help us #defeatdegeneration and join a growing proteomics team at Denali! We are looking for a highly motivated scientist to help craft quantitative proteomic assays.
Denali Therapeutics is seeking a Scientist in the Proteomics group focused on mass spectrometry based assays for preclinical and clinical studies supporting therapeutic discovery and development. Working in close collaboration with colleagues in Therapeutic Discovery, Translational Sciences, Development Sciences, and Clinical Development, the candidate will help to build qualitative and quantitative multiplexed peptide assays. This will include working closely with pathway and project scientists to identify targets of interest, build in silico models to identify proper analytes, and build optimized assays to measure the aforementioned analytes in a robust manner. The candidate will interact with scientists across the Company to lead discussions around implementation of quantitative proteomics in support of ongoing research and development projects. The candidate must have excellent communication skills and work well in a highly collaborative team environment.
Interact with pathway teams to collate and build highly multiplexed qualitative and quantitative peptide LCMS assays to elucidate significant changes in in vitro and in vivo models
The successful candidate will have a PhD with 0-3 or BS/MS degree with 5-7 years industry experience developing quantitative proteomic assays for pharmacodynamic endpoints in complex matrices.