N-Glycat Library | maryam imaninejad | 2022-08-15 11:48 | |||||||||
Hello Skyline Team, We started using InstantPC to label released mAb N-glycans to study and analyze N-glycans. For this purpose, a Waters QTof system and an MSe method were used. We could analyze our data using Skyline small molecule interface. However, this analysis was based on the precursor ion and its multicharges. As you know, some of the glycans have the same masses and using precursor ions will not let to differentiate these glycans. We are interested in using MSe and MS/MS data to correctly identify N-glycans. It seems that N-glycat library is the one that can help for this purpose. I could not find this library in your website. Not sure if it actually exists. If not, can you help us know how to use MSe data for correct ID? Is there any other library that can use MS1 and MS2 data to assign detected N-glycans? Most of the N-glycans that we are trying to identify is neutral or monosialylated. Thank you, |
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