Dear Skyline Users:
I have just released a patch to Skyline 4.2 (version 4.2.0.19072) with the following changes:

• The 32-bit installers have been fixed to again support File > Import > Results.
• The library builder has been fixed to again support PeptideShaker search results.

That's it. Thanks to the 85% of you already using 4.2 or Skyline-daily. For the remaining 15% now it is really time to UPGRADE. We are confident that 4.2 is better than its predecessors.

If you are not using Skyline 4.2 yet, please follow the manual steps to UPGRADE now. If you are already using Skyline 4.2, Skyline should ask to upgrade the next time you restart or use Help > Check for Updates.

If you are at all interested in the Skyline small molecule support, then you owe it to yourself to try Skyline-daily. It now has 3 UI modes: proteomics, small molecule and mixed (see attached). Try it and give us feedback on how you like working without all the protein and peptide references in the original Skyline proteomics-centric UI.

Enjoy using Skyline in your research.

--Brendan