Dear Skyline Users,

When we released Skyline 4.1, some users reported trouble opening small molecule documents created in version 3.7 or earlier.

We have corrected all known small molecule backward compatibility issues in the current Skyline-daily release, but not all of those fixes are in the official Skyline 4.1 release.

If you are a small molecule user still using version 3.7 due to problems you have experienced with 4.1, can you please contact me (bspratt@proteinms.net)?

If we do not hear from anyone, we will assume everyone affected is now using Skyline-daily or has found another workaround (e.g. recreating documents in 4.1), and we will not bother to include the backward compatibility fixes in our next 4.1 patch release.

Many thanks,

Brian Pratt